UYQUSIZLIK SHAROITIDA 3, 9 VA 15 OYLIK OQ KALAMUSHLAR DISTAL YO'G'ON ICHAK (CHAMBAR ICHAK) DEVORINING GISTOMORFOLOGIK ADAPTATIV-KOMPENSATOR QAYTA QURILISHI VA FITOKORREKSIYANING YOSHGA BOG'LIQ SAMARADORLIGI
Keywords:
Eksperimental uyqusizlik sharoitida 3, 9 va 15 oylik kalamushlar distal chambar ichagi devoridagi gistomorfologik adaptativ-kompensator va destruktik o'zgarishlarni baholash hamda ularni rozmarin va jenshen fitopreparatlari yordamida korreksiya qilishning yoshga bog'liq samaradorligini aniqlash.Abstract
Zamonaviy sivilizatsiyada surunkali uyqusizlik eng keng tarqalgan psixoemotsional stress omillaridan biri hisoblanadi. Uyqusizlik "bosh miya – ichak" o'qini (brain-gut axis) buzishi hamda yo'g'on ichakning morfofunksional holatiga salbiy ta'sir ko'rsatishi isbotlangan. Ayniqsa, distal chambar ichak (colon descendens) o'zining motorika, sekretor va to'siq (barrier) funksiyalarining xususiyatlari sababli stressor ta'sirlarga o'ta ta'sirchandir. biroq poststressor davrda distal chambar ichak devorining gistomorfologik adaptativ-kompensator qayta qurilishi va bu jarayonlarning yosh omiliga (3, 9 va 15 oylik) bog'liqligi hamda fitokorreksiya (rozmarin va jenshen) samaradorligi yetarlicha o'rganilmagan.
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